Abstract The relation between oxidative stress and inflammation induced by diseases and exercise has increased the interest in the benefits of antioxidant supplements in the improvement of health and physical and mental performance. The aim of this study was to evaluate the effectiveness of açai gel in reducing oxidative stress in individuals engaged in physical activities as well as their acceptance. Sensory evaluation was performed to determine its acceptability and the biochemical parameters related to immune profile and biomarkers of muscle, liver and oxidative stress, with and without the use of gel were evaluated. The appearance, sweetness and overall impression of the açai gel were considered good. It was observed a significant increase in CK enzyme, without the gel as well as the oxidative stress biomarkers, it was observed that the MDA (with and without gel) a significant increase (p < 0.05). Through biochemical evaluation, it is concluded that the gel provided protection for some of parameters studied, since it modulated the immunological parameter reducing the lymphocyte activity and muscular stress. However, more studies must be carried out with a larger number of individuals to confirm the gel functionality.

O objetivo deste trabalho é realizar um estudo preliminar para verificar a presença de resíduos de antibióticos em leite UHT disponíveis no mercado brasileiro, utilizando o método rápido do iogurte. Das 100 (100%) amostras analisadas, 96 (96%) indicaram negativas, sugerindo ausência de resíduos de antibióticos, enquanto 4 (4%) mostraram-se positivas. Os resultados sugerem a necessidade de contínuo monitoramento deste parâmetro por parte da Vigilância Sanitária com o objetivo de oferecer um produto seguro, sem riscos para saúde do consumidor.

The aim of this research was to carry out a screening study to check the incidence of antimicrobial residues in Brazilian UHT milk according to rapid yoghurt method. Of the 100 (100%) samples analysed, 96 (96%) showed no traces of antibiotic residues while 4 (4%) indicated probable presence of antibiotic residues. The results suggest that the Brazilian Sanitary Surveillance Agency should apply continuous monitoring programs in order to obtain a safe product offering no health risks to consumers.

A dieta influencia todos os estágios do ciclo da vida, fornecendo nutrientes necessários ao sustento do corpo humano. Alterações de ordem funcional e/ou estrutural, provocadas por doenças e infecções agudas ou crônicas, levam à utilização de medicamentos, cujo objetivo é restaurar a saúde. A via preferencial escolhida para a sua administração é a oral, entre outras razões, por sua comodidade e segurança. O fenômeno de interação fármaco-nutriente pode surgir antes ou durante a absorção gastrintestinal, durante a distribuição e armazenamento nos tecidos, no processo de biotransformação ou mesmo durante a excreção. Assim, é de importância fundamental conhecer os fármacos cuja velocidade de absorção e/ou quantidade absorvida podem ser afetadas na presença de alimentos, bem como aqueles que não são afetados. Por outro lado, muitos deles, incluindo antibióticos, antiácidos e laxativos podem causar má absorção de nutrientes. Portanto, o objetivo do presente artigo é apresentar uma revisão dos diversos aspectos envolvidos na interação fármaco-nutriente.

Diet influences the whole life cycle, supplying nutrients required to maintain the human body. Functional and/or structural alterations, caused by diseases and acute or chronic infections, lead to the use of drugs in order to restore the health. The oral route is preferred for drug administration, owing to safety and convenience, among other reasons. The drug-nutrient interaction phenomenon can occur before or during gastrointestinal absorption, during distribution and storage in the tissues, in the biotransformation process, or even during excretion. Thus, to know the drugs whose rate of absorption and/or absorbed amount can be affected in the presence of food, as well as those that are not affected, is of fundamental importance. On the other hand, a number of commonly used drugs, including antibiotics, antacids and laxatives, can cause malabsorption of nutrients. Therefore, the objective of this article is to present a review of the several aspects involved in the drug-nutrient interaction.